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Glossary

What is Orphan Drug Designation (ODD)?

FDA status for drugs targeting rare diseases (under 200,000 US patients) — market exclusivity plus incentives.

ODD grants seven years of market exclusivity on approval, tax credits for clinical trials, and regulatory fee waivers. It is per indication: one drug can hold many orphan designations.

Because prevalence thresholds are generous, ODD announcements are mild catalysts — the market cares far more about the data behind them.

See it live: the catalyst calendar · status-change feed

What is Orphan Drug Designation (ODD)?